ea0086oc5.6 | Metabolism, Obesity and Diabetes | SFEBES2022
Bany Bakar Rula
, Sayda Mariwan H.
, Smith Christopher A.
, Guccio Nunzio
, Kay Richard
, Gribble Fiona M.
, Reimann Frank
Backgrounds and aims: Enteroendocrine cells (EECs) are hormone-secreting cells within the intestinal epithelium that play an important role in regulating food absorption, insulin secretion and appetite. The somatostatin (SST)-producing D-cell is an EEC of particular interest due to the profound inhibition exerted by SST over other EECs, highlighting D-cells as critical regulator of the enteroendocrine axis. The aim of this study was to profile the transcriptom...